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7.12. Endocrine disorders.

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MIL-therapy is effective in the treatment of Diabetes mellitus type II, hypothyreosis of various genesis and other endocrine disorders. It may be applied as an independent method as well as in the combination with traditional medicamentous therapy. MIL-therapy for endocinological diseases should be conducted only by an endocrinologist trained in laser therapy and after thorough patient’s examination. Constant biochemical control (blood and urine glucose levels, their daily fluctuations, C-peptide, immune reactive insulin, T3, T4, TTG, cortizol) and clinical control are performed during MIL-therapy course .

Diabetes mellitus

The main task of modern medicine is to arrest progressing both the disease itself and its complications (for instance, distal diabetic polyneuropathy is seen in 10-80% of patients). It has been shown that laser therapy (especially without drugs - as a monotherapy) is very effective for improving the state and conductivity of injured nervous fibres, microcirculation in tissues and organs, hormonal balance , CNS functions, immunity.

The terminal is put (Fig. 32) onto the skin of the front abdominal wall at the pancreas projection (zone 5) ( irradiation through the lumbar area is not recommended due to a possible stimulation of adrenal cortex and contrainsular corticosteroid effect ) and on the lower ribs to the right (zone 4). Exposure is 2 min on each area with a gradual increase up to 5 min. by the 4-5th session. After that the thymus projection (zone 3) and the left subclavicular vascular bundle (zone 2) are irradiated for 2 min at each zone. Impulse frequency is 50 Hz, LED radiation power is 70 mWt. The course consists of 10 -12 procedures every other day.

Slight elevation of blood sugar level is seen in practically all patients immediately after the first procedure. After 3-4 sessions it goes down both in blood and urine. It has been noted that definite changes of reflection coefficient in tissues revealed at biophotometry during the treatment correlate with daily fluctuations of sugar level in blood. This indicator helps to individualise the course of treatment. Blood sugar level in type II diabetes ( both under the administration of antidiabetic drugs and without it) decreases by 1,5-2 times; it also depends on the patient’s compensatory mechanism. Reduction of the amplitude of daily blood sugar level under MIL-therapy is a favourable prognostic sign. The course of MIL-therapy may be repeated in 3-4 months.

Diabetic angiopathy of the lower extremities (trophic ulcers)

A thorough diabetes compensation (medicamentous, laser) is provided preliminary to MIL-therapy. Hemotripsin, Solcoseril ointment , Actovegin ointment are appplied topically . After that the left subclavicular area (zone 2) and the inguinal vascular bundles (zones 6) are irradiated for 2 min. each, the thymus projection (zones 3) is irradiated for 1 min. (Fig. 32) (frequency 50 Hz, LED IR radiation power 60 mWt) . Procedures are performed every other day, 10-12 procedures for the course.

A clinical effect (ulcer epithelization, elimination of painful sensations) is maximally evident by the 8-10th procedure. Reduction of antiaggregant medicine is possible by the 5-6th procedure. Heparin dosage is gradually decreased and by the 3-4th procedure it may be cancelled. Topical drugs (except drying substances) are cancelled at the beginning of epithelization process . No side effects have been registered. The basic effect is the inhibition of free radical processes ( more than by 2 times) which is correlated with patient’s state and may be a criterion of treatment adequacy.

Diabetic retinopathy

Fluorescent lymphoangioscopy reveals a significant damage of lymph circulation in patients with this pathology (moderate filling the level of which depends on the duration of the diabetes mellitus and the extension of destructive changes in the retina and choroidal membranes). MIL-therapy effects lymph circulation in the bulbar conjunctiva in patients with pre-proliferative diabetic retinopathy (type II diabetes mellitus): indexes of lymphatic drainage in the eye are improved.

The terminal is put (Fig.33) on the left subclavicular vascular bundle projection (zone 2), on the left carotid projection (zone 1). Impulse frequency is 150 Hz, LED radiation power is 70 mWt, exposure is 2 min on each zone. Then the sympathetic nodes on the neck are irradiated bilaterally for 1 min. Procedures are performed every other day (7-8 for the course). MIL-therapy course may be repeated in 1-3 months.

Fig. 33. Zones of MIL-irradiation for treating diabetes mellitus
Hypothyreosis ( after the autoimmune thyroiditis, after a partial resection of the thyroid gland, etc.)

MIL-therapy combined with pharmacotherapy is extremely effective in such diseases, especially at their initial stages as well as at the neurologic syndrome: after few first sessions patients note “clarity in the head”, reduction of fatigability, better physical and psychological state. By the end of MIL-therapy course there appears a significant decrease in the emotional liability and mood fluctuations, a marked improvement of psychic and motional activity. However, a tendency for recurrences is still preserved. That is why curative-prophylactic, antirecurrent courses of MIL-therapy are recommended every 2-3 months (3-4 courses). MIL-therapy is performed as an independent method or in combination with L-thyroxin substitution therapy.

The first variant: the terminal is put (Fig. 33) on the thyroid gland area (zones 1) consecutively on both lobes with the exposure 1 min. Then zones to the right and to the left from the 7th neck vertebrae (zones 6) are irradiated for one minute. After that the liver (zone 7) and the pancreas (zone 8) are irradiated for 2 min on each zone. Impulse frequency is 50 Hz, LED radiation power is 75-80 mWt. Procedures are performed every other day, 10-12 procedures for the course.

During MIL-therapy one can observe normalization of clinical signs (hypodynamics, bradycardia). Reflexometric data are improved too. Cortizol level in blood goes up right after the first session (blood sampling is done 30-40 min. after MIL-therapy session). Further a thorough selection of doses and irradiation repetitions eradicate this reaction. After 4-5 sessions there appears the increase of threeiodthyronin (T3) content with a simultaneous decrease of tetraiodthyronin (T4) content in blood. The patients who are prescribed L-thyroxin (in a constant dosage) and MIL-therapy have less pronounced fluctuations in T3 and T4 levels than patients who have only MIL-therapy. However, at the same time one can observe a significant reduction in the hypophysis thyrotropic hormone (TTG) level; this fact demonstrates an effective stimulation of the hormone in glandular tissue.

If the first course of MIL-therapy is effective, the repeated course is recommended in 3-4 months under the control of patient’s endocrine status.

The second variant: MIL-sessions are performed every other day. The area of the left subclavicular vascular bundle (zone 4) (Fig.33) is irradiated with the impulse frequency 10 Hz, LED radiation power 60 mWt; exposure 10 min. After that the 7th neck vertebrae (zone 6), the front temporal areas (zones 2, 3) and both thyroid lobes (zone 1) are irradiated alternatively, for 15 sec. Impulse frequency is 80 Hz, LED radiation power is 60 mWt. 10 - 20 procedures for the course. This variant is more preferable in patients with evident nervous and psychic disturbances.

Fig. 34. Zones of MIL-irradiation for treating thyroid gland pathologies
Climacteric syndrome

Gynecologists-endocrinologists consider the climacteric syndrome to be a natural physiological process characterized by the extinction of gonadotropic function of the front hypophysis lobe and by the impairments in coordination with the ovarial-adrenal system.

MIL-therapy normalizes blood hormonal level, central regulation of the endocrine system. It also significantly increases psycho-emotional status and improves the quality of life.

The curative terminal is put (Fig. 34) on the area of apical stroke (zone 2) and on the left subclavicular vascular bundle projection (zone 1). Impulse frequency is 5 Hz, LED radiation power is 30 mWt, exposure is 5 min on one zone. Then the liver (zone 3) and the pancreas (zone 5) are irradiated with frequency 80 Hz and LED radiation power 40 mWt, exposure 2 min. This irradiation is done paravertebrally at LIII-LIV (zones 4) level for 30 sec. (frequency 600 Hz, LED radiation power 40 mWt). 8-10 daily procedures for the course. The course is repeated under the same scheme one month later.

With climax advancing in men and women there appear manifestations of a number of different diseases including cardio-vascular, urologic, gynecologic, metabolic, psycho-neurologic ones. So, in 6 months after these two MIL-therapy courses a patient may require a new MIL-therapy course for treating the revealed accompanying pathology. Such treatment is performed according to the schemes described in the present Instructions (see the corresponding articles).

Fig. 35. Zones of MIL-irradiation for treating climacteric syndrome and hormonal disturbances
Laser therapy and hormonal therapy

Lately, hormones of the hypophysis, adrenal cortex and others have been widely used for treating asthma, ulcerative colitis, rheumatism and other pathologic processes in men. However, the longer lasts the endocrine dysfunction caused by this therapy, the more expressed are psychic disturbances even up to the development of so-called “steroid psychosis”. Sensation of energy, constant euphoria may quickly transform to depression, prostration and other negative states.

Curative-adaptive mechanisms of LILR irradiation are used to protect human organism of hormonal therapy side-effects (in combination with medicamentous preparations but with gradual reduction of their doses).

MIL-therapy is performed every other day (Fig. 34). The left subclavicular area (zone 1) is irradiated with 10 min. exposure (impulse frequency 10 Hz, LED radiation power 60 mWt). Zones of the carotid projection ( zone 6 on each side), of the thymus projection (zone 8) are irradiated simultaneously, 1 min on one zone ( zone 1 is irradiated every other day). Then MIL-irradiation is done to the sites of somatic injury (gastritis, colitis, asthma, etc.) and to the liver projection (zone 3) for 2 min on each zone; then the 7th neck vertebrae (zone 7), the adrenal glands projection (zones 9) with exposure 15-30 sec., impulse frequency 80 Hz, LED radiation power 40 mWt. Total time for one procedure is not more than 10 min. The course of treatment consists of 5-10 such procedures.

MIL-therapy in this pathology has the aim to reduce the dosage of hormonal medicamentous preparations, to control symptoms of endocrine dysfunctions. One month later a new course of MIL-therapy may be started to treat a basic disease using the developed, tested scheme.